In contrast, for type B AAD endovascular repair has been more frequently adopted in recent years but without a significant demonstrable reduction of in hospital mortality, although an increased survival rate at 5 years was observed. Data shows trend for a reduced overall in hospital mortality over the years, in particular for those operated on for type A AAD, due to the improvement in operative technologies, organ perfusion and surgeons taking on even high-risk patients.
After 20 years of enrollment, more than 8000 patients with AAD have been collected worldwide, roughly two-thirds with type A and one-third with type B. Acute aortic dissection, including intramural hematoma, is defined as onset of symptoms within 14 days to hospital admission. The International Registry of Acute Aortic Dissection (IRAD) is an ongoing registry, which was established in 1996 with the aim to collect data and provide information on this rare disease in order to provide better decision making on clinical practice and surgical management. In this article we review lessons learned from the 20-year IRAD Registry experience and its nearly 100 publications. It is associated with high morbidity and mortality rates, in spite of new management approaches developed over the past few decades. Louis, MO, USA 6 Sant’Orsola University Hospital, University of Bologna, Bologna, Italy 7 Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA 8 Department of Clinical Medicine, Tromso University Hospital, Tromso, Norway 9 Department of Thoracic Surgery, Cardiovascular Center, University of Michigan, Ann Arbor, MI, USAĪcute aortic dissection (AAD) is a life-threatening disorder that is challenging to diagnose and with defined optimal therapies and outcomes. EAGLE 9, on behalf of the International Registry of Acute Aortic Dissection (IRAD) Participantsġ Section of Vascular Surgery, Department of Clinical Science and Community Health, Maggiore Polyclinic Hospital, Ca’ Granda IRCCS and Foundation, University of Milan, Milan, Italy 2 Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA 3 Robert Bosch Hospital, Stuttgart, Germany 4 Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria 5 Washington University School of Medicine, St. BRAVERMAN 5, Davide PACINI 6, Marc SHERMERHORN 7, Truls MYRMEL 8, Kim A. Language: English Lesson learned from the International Registry of Acute Aortic Dissection (IRAD)Ĭhiara LOMAZZI 1 ✉, Santi TRIMARCHI 1, Reed E.
REVIEW THORACIC AORTIC CHALLENGES Italian Journal of Vascular and Endovascular Surgery 2020 March 27(1):15-25
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